He sighed with profound resignation.是什么意思？

He sighed with profound resignation.

他极其无奈地叹了一口气。

he

pron. 他，它，一个人；n. 雄性动物；

例句
Logic had prevailed and he had abandoned the idea.
最终理智占了上风，他打消了那个念头。

sighed

v. 叹气，叹息( sigh的过去式和过去分词 )，悲鸣，叹着气说，叹息道；

例句
She sighed and flicked a dishcloth at the counter...
她叹了一口气，然后用洗碗布轻掸着柜台。

with

prep. 和，跟，随着，关于，和…一致；

例句
A waiter entered with a tray...
侍者端着托盘进来了。

profound

adj. 深厚的，意义深远的，严重的，知识渊博的；n. 〈诗〉深海，大洋，深渊，（灵魂）深处；

例句
If the world is to avoid environmental catastrophe, advanced economies must undergo a profound transition.
世界若要想避免环境灾难，经济发达的国家必须进行深刻变革。

resignation

n. 辞职，辞职书，顺从，听从；

例句
The President's resignation appears to be an acknowledgment that he has lost all hope of keeping the country together...
总统的辞职似乎表明他对维护国家稳定已不抱任何希望。