[zhōu zhé]
twists and turns; setbacks; a complicated [troublesome] course of development; trouble; complication; tortuous course
cause a lot of trouble
大费周折
Only after many setbacks was success achieved.
几经周折才告成功。
Since that time there has never been any setback in his career.
从那时起他在事业上一直没有遇到周折。